Meiosis and oogenesis

Meiosis and oogenesis

How does the follicle coordinate meiosis progression? The ovarian follicle is an integrated system in which follicular cells regulate oocyte progression into meiosis. Oocytes are large cells that divide asymmetrically to preserve stores for future embryonic development. To do this, they must coordinate asymmetric spindle positioning with cell cycle progression and chromosome segregation. In mam...

Oogenesis: Making the Mos of Meiosis

Meiosis is an ancient type of cell division whose advent allowed the evolution of sexual reproduction. The evolutionary history of the specialization that allowed gamete production to emerge from a simple reduction division has been unclear. New data now suggest that the molecular mechanisms involved in animal oocyte specialization may have origins that predate the emergence of bilaterian animals.

The Timing of Meiosis and Dna Synthesis during Early Oogenesis in the Toad, Xenopus Laevis

Recently metamorphosed female Xenopus laevis toads were injected with tritiated thymidine. Animals were kept at 20 degrees C and were sacrificed 1-23 days after isotope injection. Radio-autographs of squash preparations of the ovaries were made. The progress of labeled germ cell nuclei was followed to obtain information on the time course of early meiosis and extra-chromosomal DNA synthesis. Pr...

Drosophila Inducer of MEiosis 4 (IME4) is required for Notch signaling during oogenesis.

N(6)-methyladenosine is a nonediting RNA modification found in mRNA of all eukaryotes, from yeast to humans. Although the functional significance of N(6)-methyladenosine is unknown, the Inducer of MEiosis 4 (IME4) gene of Saccharomyces cerevisiae, which encodes the enzyme that catalyzes this modification, is required for gametogenesis. Here we find that the Drosophila IME4 homolog, Dm ime4, is ...

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